The Inhibitory Effect of HDACI on Cellular Migration in the Breast Cancer Cells

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We investigated the effects of Panobinostat (LBH-589), suberoylanilide hydroxamic acid (SAHA), and valproic acid (VPA) as histone deacetylase inhibitors (HDACI) and 5-aza-2ʹ-deoxycytidine as a methyltransferase inhibitor on the migratory capacity of the breast cancer cell line MDA-MB-231. Methods:  Cell migration assays were performed using an in vitro agarose spot assay as described by (Wiggins and…

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Induction of Apoptosis by Tannin

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Cellular stress induces apoptosis. This stress should not be radioactive, chemical stress, inappropriate keeping conditions or viral infection. Cellular damage or cellular stress can only develop through lack of diet. The described manganese diets caused by tannin can suppress the normal function of anti-apoptotic proteins, paving the way for the activation of apoptosis Perhaps the…

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Intestinal Mucosal Immunology in Poultry

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Mucosal Immunology is considered a new field of immunology. Mucosal immunology focuses on the aspects by which the antigens can enter the mucosal surface of the gastrointestinal tract The intestine is a large contact surface to the outside; the intestinal epithelial cells not only produce multiple immunoregulatory cytokines, but also can alter the activity of…

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